The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in miceArticle Published on 2023-01-172023-07-11 Journal: Cell Reports Medicine [Category] COVID19(2023년), [키워드] ADCC convalescent plasma COVID-19 Fc-effector IgA IgG IgM macrophages neutrophils. SARS-CoV-2 [DOI] 10.1016/j.xcrm.2022.100893 PMC 바로가기
Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary InfectionArticle Published on 2022-12-212023-07-10 Journal: mSphere [Category] COVID19(2023년), [키워드] IgA IgG mucosal immunity SARS-CoV-2 systemic response vaccination. [DOI] 10.1128/msphere.00279-22 PMC 바로가기
Humoral immunity and B-cell memory in response to SARS-CoV-2 infection and vaccinationArticle Published on 2022-12-162023-07-10 Journal: Biochemical Society Transactions [Category] COVID19(2023년), [키워드] COVID-19 IgG memory B cell neutralizing antibody. omicron SARS-CoV-2 [DOI] 10.1042/BST20220415 PMC 바로가기
Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infectionArticle Published on 2022-12-092023-07-10 Journal: Med (New York, N.Y.) [Category] COVID19(2023년), [키워드] BA.5 breakthrough IgA IgG mucosal immunity neutralization omicron SARS-CoV-2 Translation to patients Vaccine variants. [DOI] 10.1016/j.medj.2022.09.010 PMC 바로가기
Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2기계 학습과 결합된 펩티드 마이크로어레이는 SARS-CoV-2에 대한 중화 기능을 가진 인간 항체 반응의 개별 에피토프를 나타냅니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료법, [키워드] anti-SARS-CoV-2 antibody Antibody binding assays binding epitope capture causative agent cellular coronavirus coronavirus SARS-CoV-2 Course COVID-19 detectable epitope Epitopes human antibody response IgA IgG IgM antibody immunoassays incubated infected with SARS-CoV-2 machine learning Microarray N-terminus negative control samples neutralization neutralization assays Neutralizing Neutralizing antibodies nine overlapping Patient peptide peptide arrays peptides positive protective effect Protective effects random Random forest response S protein SARS CoV SARS CoV-2 SARS-CoV-2 sera serology Serology. Specific structural protein structural proteins the disease the S protein vaccine candidate vaccine candidates Viral [DOI] 10.1080/22221751.2022.2057874 PMC 바로가기 [Article Type] Article
Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice근육내 및 비강내 상동 프라임-부스트를 침팬지 아데노바이러스 기반 COVID-19 백신과 결합하면 마우스에서 강력한 체액성 및 세포성 면역 반응을 이끌어냅니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adenovirus adenovirus-based Adenovirus-vectored vaccine Administered antibody titres approach BALB/c mice booster Cellular immune response ChAdTS-S coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines cytokine decrease Efficacy elicit elicited evaluated followed by group highest homologous humoral IFN-γ IFN-γ ELISPOT IgA IgG immune immune responses immunogenicity intracellular cytokine staining intramuscular intramuscular vaccination intranasal intranasal. Meso Scale Discovery mice prime immunization priming protocol provide pseudovirus neutralizing antibody respiratory responsible SARS-CoV-2 serotype shown T-cell Response T-cell responses tested titre vaccination Vaccine variants vectored vaccine [DOI] 10.1080/22221751.2022.2097479 PMC 바로가기 [Article Type] Article
Possibility of underestimation of COVID-19 prevalence by PCR and serological testsArticle Published on 2022-12-012023-07-06 Journal: Journal of microbiology, immunology, and infection [Category] COVID19(2023년), [키워드] COVID-19 IgG PCR Prevalence SARS-CoV-2 Serological test. [DOI] 10.1016/j.jmii.2021.09.005 PMC 바로가기
Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIVHIV 보균자에서 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성Observational Study Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] adverse event age Analysis binding domain booster dose CD4 CD4 count CD4 counts Cell COVID-19 declined Efficacy enrolled evaluated Factor Frequency Gender geometric GMT healthy control healthy controls HIV humoral humoral immune response IgG immune immune response Immunocompromised in both groups inactivated Inactivated vaccine less MBC memory B occurred Patient PLWH predicted prospective observational study reduced remained reported response responses robust Safety Safety. SARS-CoV-2 SARS-CoV-2 vaccine Serious Adverse Event Seven significantly vaccination Viral load with HIV [DOI] 10.1080/22221751.2022.2059401 PMC 바로가기 [Article Type] Observational Study
Immunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primatesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accompanied Blood clinical investigation Coverage COVID-19 COVID-19 pandemic COVID-19 vaccine cytokine release Diseases effective effort elicit Gam-COVID-Vac Health heterologous prime-boost IgA antibody IgG immune response Immunity immunization immunogenic immunogenicity Infection intranasal intranasal vaccine. intranasally K18-hACE2 transgenic mice less lung immunopathology mice mononuclear cell Mortality mucosal nasal mucosa neutralizing antibody non-human primate pandemic Peripheral blood Prevent proliferation protective immunity provided revaccination robust SARS-CoV-2 SARS-COV-2 infection SARSCoV-2 serum Sputnik V systemic and local the vaccine Transmission vaccination Vaccination strategy Vaccine vaccine candidate variants of concern virus virus infection virus spread [DOI] 10.1080/22221751.2022.2119169 PMC 바로가기
B cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses강력하고 불량한 SARS-CoV-2 백신 반응과 관련된 B 세포 수용체 신호Article Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] age antibody Antibody Response B cell B cell receptor Biomarker class switch recombination clone Cohort COVID-19 healthy IgG IgM Immunity inactivated Inactivated vaccine inactivated vaccine. individuals Infection molecular mRNA Neutralizing antibodies receptor recipient Reinfection response SARS-CoV-2 SARS-CoV-2 vaccine the antibody response vaccinated individual vaccination Vaccination strategies vaccine-induced antibody response [DOI] 10.1080/22221751.2022.2030197 PMC 바로가기 [Article Type] Article